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Table 1 Illustrative example: a hypothetical cohort study of the relationship between low aspirin intake and polyps among individuals with and without the high-risk COX-2 genotype

From: Distributional interaction: Interpretational problems when using incidence odds ratios to assess interaction

 

Individuals with high-risk COX-2 genotype

Individuals without high-risk COX-2 genotype

 

Polyps

No Polyps

Polyps

No Polyps

Low aspirin intake

75

25

30

70

High aspirin intake

25

75

10

90

Risk Ratio

3.0

3.0

Odds Ratio

9.0

3.9