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Table 2 Example from Li et al: "A common polymorphism in XRCC1 as a biomarker of susceptibility for chemically induced genetic damage" [11]

From: Distributional interaction: Interpretational problems when using incidence odds ratios to assess interaction

 

Individuals with XRCC1 high-risk genotype (Gln – Gln)

Individuals with XRCC1 low-risk genotype (Arg – Arg)

 

p53+

p53-

p53+

p53-

High vinyl chloride exposure (>4000 ppm-yrs)

8

2

11

20

Low vinyl chloride exposure (≤1000 ppm-yrs)

5

6

6

18

Risk Ratio

1.76

1.42

Odds Ratio

4.80

1.65