Table 5 Colon cancer relative risk associated with BMI (kg/m²), by NSAID/aspirin and HRT use,1991–1994

BMI

≤ 23

202/307

1.0

41/115

161/192

1.0

2.4 (1.6,3.6)

24–25

233/296

1.2 (0.9–1.5)

71/120

162/176

1.6 (1.02,2.6)

2.5 (1.6,3.8)

26–29

459/528

1.3 (1.0–1.6)

136/189

323/339

1.9 (1.3,3.0)

2.6 (1.7,3.8)

≥ 30

443/404

1.6 (1.2–2.0)

179/177

264/227

2.7 (1.8,4.1)

3.0 (2.0,4.5)

RERI²(95% CI); p value

-1.09 (-2.30, 0.11); 0.07

HRT³

Everyone

Adjusted

Yes

No

Yes

No

BMI

≤ 23

109/145

1.0

27/64

82/81

1.0

2.6 (1.5,4.6)

24–25

97/109

1.2 (0.8–1.7)

39/44

58/66

2.1 (1.1,4.0)

2.3 (1.3,4.1)

26–29

139/151

1.2 (0.9–1.7)

35/49

105/102

1.7 (0.9,3.3)

2.6 (1.5,4.5)

≥ 30

137/154

1.1 (0.8–1.5)

37/41

100/113

2.1 (1.1,4.0)

2.1 (1.2,3.5)

RERI⁴ (95% CI); p value

-1.68 (-3.53,0.17); 0.07