Table 3 Illustrative examples of FIS and SCDS BNT results corrected for unaccounted confounding
Scenario | Confounder SD | Confounder Correlation with | Regression slope | ||
|---|---|---|---|---|---|
| Â | Â | Exposure | Outcome | Observed | Corrected |
FIS | Â | Â | Â | Â | Â |
Scenario 1 | 15.0 | -0.10 | 0.20 | -0.019 | -0.015 |
Scenario 2 | 15.0 | 0.10 | 0.20 | -0.019 | -0.023 |
Scenario 4 | 15.0 | -0.50 | 0.20 | -0.019 | 0.002 |
Scenario 3 | 15.0 | 0.50 | 0.20 | -0.019 | -0.053 |
Scenario 5 | 15.0 | -0.10 | 0.80 | -0.019 | -0.002 |
Scenario 6 | 15.0 | 0.10 | 0.80 | -0.019 | -0.036 |
Scenario 7 | 15.0 | -0.50 | 0.80 | -0.019 | 0.085 |
Scenario 8 | 15.0 | 0.50 | 0.80 | -0.019 | -0.136 |
SCDS | Â | Â | Â | Â | Â |
Scenario 1 | 15.0 | -0.10 | 0.20 | -0.012 | 0.01 |
Scenario 2 | 15.0 | 0.10 | 0.20 | -0.012 | -0.03 |
Scenario 3 | 15.0 | -0.50 | 0.20 | -0.012 | 0.13 |
Scenario 4 | 15.0 | 0.50 | 0.20 | -0.012 | -0.16 |
Scenario 5 | 15.0 | -0.10 | 0.80 | -0.012 | 0.07 |
Scenario 6 | 15.0 | 0.10 | 0.80 | -0.012 | -0.10 |
Scenario 7 | 15.0 | -0.50 | 0.80 | -0.012 | 0.55 |
Scenario 8 | 15.0 | 0.50 | 0.80 | -0.012 | -0.58 |